The leading resource in tourism is certainly the geographic space where tourist market offer is formed and at the same time where integrated tourism products are consumed. Tourism regionalization is only partly based on the standard criteria of geographic regionalization, which is justified in view of the specificity of tourism, the particularity of determining the boundaries of the tourist region, as well as other motives and reasons. The imperative of this is the tourist regionalization of the world issued by the World Tourism Organization. Based on this regionalization, Europe is recognized as the dominant dynamic category. Europe is the leading emitive and receptive tourist market on an international level. Since most countries of Europe are integrated into a supranational creation, the European Union, this status is justified to link to the same. The development of European Union tourism is directly supported by a highly elaborate, stable and efficient institutional framework. It is about the existence of numerous bodies or institutions that focus on the design, stability and competitiveness of tourism. The leading institutions are Commission and Parliament, but the contribution and the impact of other institutions and specialized organizations should not be ignored. Tourism is in many ways a specific and very complex socio-economic phenomenon. Among other things, this is confirmed by the complexity of the European Union's initiatives aimed at planning, managing development, business, but also controlling and developing it. It can be concluded that these are strategic issues or areas in the context of sustainable tourism development. In this way, the European Union ensures a stable environment in tourism, simplifies complex operations and demanding development, and at the same time creates the basis for a readiness to respond to future challenges and changes.