Healthcare workers are under a lot of stress due to the heavy workload, working hours, lack of employees they face, and for the past three years they have been faced with additional stress and burnout at work due to the COVID-19 pandemic. The aim of the research was to examine whether there is a difference in the perception of stress and the consumption of anxiolytics among healthcare workers in hospital and outpatient settings. The research was conducted through a voluntary anonymous online survey, and included 113 respondents, that is, nurses and technicians, doctors and other health workers in Pula, of which 30 were male and 83 were female. Anxiolytics are taken by 15% of the respondents, and there is no statistically significant difference between inpatient and outpatient health workers, doctors and nurses, but there is a statistically significant difference regarding the respondent's workplace and experience of stress. 92.9% of employees perceive their work as stressful, 9.7% sought the help of a psychologist or psychiatrist, and 66.4% believe that workplace conditions contribute to the use of anxiolytics. The most stressful factor is work organization and financial issues. It was concluded that there is no significant difference in the consumption of anxiolytics between healthcare workers in hospital and outpatient settings, but the perception of stress is higher among those employed in the outpatient sector.