This thesis deals with the persecution of witches in Croatia and Europe in the Middle Ages and the early Modern Age. The thesis begins by defining the term 'witch' and the conception of their actions. Given the fact that the Church was the one that initiated the hysteria of witch persecution, and was the only one dealing with this problem at the beginning, we will show how the secular authorities began to engage with the problem. The thesis presents laws, documentary records, manuals and books relevant to the witchcraft process. It also gives an overview of the Inquisition actions and court procedures against the heretics, as well as the forms of torture used in the investigation of the accused. At the end of the thesis we give an insight on the ending of the persecution in Croatia and we conclude that the reason for the massive persecution was superstition and human malice.